4-Piperidinemethanamine, N,N-dimethyl-

4-Piperidinemethanamine, N,N-dimethyl- - Names and Identifiers

Name	N,N-Dimethyl-1-piperidin-4-ylmethanamine
Synonyms	N,N-Dimethyl-1-(piperidin-4-yl) 4-Piperidinemethanamine, N,N-dimethyl- N,N-Dimethyl-1-piperidin-4-ylmethanamine N,N-Dimethyl-1-piperidin-4-ylmethylamine N,N-DIMETHYL-1-PIPERIDIN-4-YLMETHANAMINE N,N-dimethyl-1-(4-piperidinyl)methanamine
CAS	138022-00-1
InChI	InChI=1/C8H18N2/c1-10(2)7-8-3-5-9-6-4-8/h8-9H,3-7H2,1-2H3

4-Piperidinemethanamine, N,N-dimethyl- - Physico-chemical Properties

Molecular Formula	C8H18N2
Molar Mass	142.24
Density	0.868±0.06 g/cm3(Predicted)
Boling Point	178.8±8.0 °C(Predicted)
Flash Point	51.809°C
Vapor Presure	0.973mmHg at 25°C
pKa	10.53±0.10(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.451

4-Piperidinemethanamine, N,N-dimethyl- - Risk and Safety

Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Hazard Class	IRRITANT

4-Piperidinemethanamine, N,N-dimethyl- - Introduction

4-(Dimethylaminomethyl) piperidine, also known as DMAP, is an organic compound. The following is a description of the nature, use, formulation and safety information of DMAP:

Nature:
-Appearance: DMAP is colorless or yellowish crystal.
-Solubility: DMAP is soluble in most organic solvents, such as alcohols, ethers and ketones, but insoluble in water.
-Aroma: DMAP has a strong amine odor.

Use:
-Catalyst: DMAP is often used as a catalyst in organic synthesis, especially in esterification, amide formation and initiation of condensation reactions.
-Drug synthesis: DMAP is widely used in drug synthesis reactions, such as the synthesis of antibiotics and other organic compounds.
-Preservative: Because DMAP has an inhibitory effect on microorganisms, it is often used as a preservative additive.

Preparation Method:
The preparation of DMAP is usually carried out by the following steps:
1. Reaction of N,N-dimethylaminomethanol with piperidine.
2. Heat the reaction in an appropriate solvent to obtain DMAP.

Safety Information:
- DMAP is an irritant and may cause irritation to the eyes, skin and respiratory tract. During use, wear appropriate personal protective equipment to avoid contact with skin and eyes.
- DMAP should be stored in a cool, dry, well-ventilated place, away from fire and oxidizing agents.
-When using DMAP, please follow the correct laboratory procedures and carefully consult the relevant chemical safety data sheet (SDS) for detailed safety information and operating instructions.

Please note that the laboratory should follow the correct safety procedures when handling chemicals, and need to understand the detailed chemical characteristics and safety information before use.

Last Update：2024-04-09 21:04:16